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Case Reports of Severe Paediatric Sickle Cell Retinopathy: Disease Manifestations, Progression and Treatments

Evdokia Sourla1, Peck Lin Lip1

  • 1Birmingham and Midland Eye Centre, Sandwell & West Birmingham Hospitals NHS Trust, Birmingham, UK.

International Medical Case Reports Journal
|August 8, 2024
PubMed

Insights

Severe sickle retinopathy, though common in adults, is less understood in children. This report details two pediatric cases, highlighting treatment challenges and the benefits of laser photocoagulation for early sickle proliferative disease.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Hematology

Background:

  • Sickle retinopathy is a known complication in adult sickle cell disease patients.
  • Limited data exists on sickle retinopathy presentation and management in pediatric populations.

Observation:

  • Two pediatric patients (12 and 13 years old) with sickle cell disease presented with severe sickle retinopathy.
  • Disease progression and treatment outcomes were monitored over 2-3 years.

Findings:

  • Laser photocoagulation demonstrated benefits in treating early sickle proliferative disease.
  • Advanced retinopathy complications presented significant challenges to effective treatment in these young patients.

Implications:

  • This case series underscores the importance of early detection and intervention for sickle retinopathy in children.
  • Effective management strategies are crucial to prevent vision loss in pediatric sickle cell patients.

Keywords:
childrenlasersalmon patchseafanstractionvitreous hemorrhage

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