Renal Mucormycosis with Disseminated Lytic Bony Lesions

Vignesh Subramani1, Jasmine Sethi1, Vaishnavi Venkatasubramanian1

  • 1Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

PubMed

Insights

Renal mucormycosis is a deadly fungal infection causing tissue damage. Early antifungal treatment and surgery are crucial for diabetic patients with this severe pyelonephritis.

Area of Science:

  • Nephrology
  • Mycology
  • Oncology

Background:

  • Renal mucormycosis is a rare, invasive fungal infection.
  • It is associated with high mortality and extensive tissue damage.

Observation:

  • A case of disseminated fungal pyelonephritis in a diabetic patient is presented.
  • The patient exhibited extensive lytic bone lesions that mimicked malignancy.

Findings:

  • The fungal infection led to significant renal tissue invasion and infarction.
  • The presentation mimicked metastatic cancer due to lytic bone lesions.

Implications:

  • Prompt antifungal therapy and surgical debridement are vital for managing renal mucormycosis.
  • Clinicians must maintain a high suspicion for mucormycosis in non-resolving pyelonephritis with prolonged fever, especially in diabetic patients.