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Strategies for the prevention of bronchopulmonary dysplasia

Gianluca Dini1, Sara Ceccarelli1, Federica Celi1

  • 1Neonatal Intensive Care Unit, Santa Maria Hospital, Terni, Italy.

Frontiers in Pediatrics
|August 8, 2024
PubMed

Insights

Bronchopulmonary dysplasia (BPD) is a common issue for preterm infants, causing long-term disabilities. This review explores current evidence on preventing BPD, offering practical clinical insights.

Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology

Background:

  • Bronchopulmonary dysplasia (BPD) is a frequent complication in preterm infants.
  • BPD is linked to significant long-term health issues and varied clinical presentations.
  • The causes of BPD are complex and multifactorial.

Purpose of the Study:

  • To review current evidence on preventing BPD in preterm infants.
  • To offer practical guidance for clinicians managing BPD risk.
  • To synthesize recent research on BPD pathogenesis and prevention.

Main Methods:

  • Literature review of recent studies on BPD prevention.
  • Analysis of factors contributing to BPD development.
  • Synthesis of clinical trial data and observational studies.

Main Results:

  • Current understanding of BPD pathogenesis has advanced.
  • Effective prevention and management strategies remain challenging.
  • Evidence for specific preventive interventions is still evolving.

Conclusions:

  • Preventing BPD in preterm infants requires a comprehensive approach.
  • Further research is needed to refine prevention strategies.
  • Clinical practice should integrate the latest evidence for optimal outcomes.

Keywords:
bronchopulmonary dysplasialung diseaseneonatal carepostnatal corticosteroidspreterm infants

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