Related Experiment Video
Updated: Jun 17, 2025
Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
Published on: June 18, 2020
[Serum hyperviscosity syndrome: Update 2024].
Pierre-Edouard Debureaux1, Nathalie Parquet2, Anne C Brignier2
1Service immuno-hématologie, hôpital Saint Louis, Paris, France; Université Paris Cité, institut de recherche Saint-Louis, Inserm U1160, Paris, France.
Seric hyperviscosity syndrome, a medical emergency caused by high blood protein levels, presents with bleeding, vision, and neurological issues. Prompt diagnosis via fundoscopy and treatment with therapeutic plasma exchange are crucial.
Area of Science:
- Hematology
- Oncology
- Internal Medicine
Context:
- Seric hyperviscosity syndrome is a critical condition associated with hyperproteinemia.
- Clinical presentation includes mucosal hemorrhages, visual disturbances, and neurological deficits.
Purpose:
- To outline the diagnostic criteria and management strategies for seric hyperviscosity syndrome.
- To identify the common etiologies of this medical emergency.
Summary:
- Diagnosis relies on a triad of symptoms and is confirmed by fundoscopic examination.
- Therapeutic plasma exchange is the mainstay treatment for severe or confirmed cases.
- Waldenström's macroglobulinemia, multiple myeloma, and cryoglobulinemias are the primary underlying causes.
Impact:
- Highlights the urgency of diagnosis and intervention in hyperviscosity syndrome.
- Emphasizes the importance of identifying and treating the underlying plasma cell disorder.
- Provides a framework for managing this life-threatening hematological emergency.
More Related Videos
04:00Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
Published on: November 15, 2024
05:44Author Spotlight: Utilizing Venoplasty Balloon Model in Rodents to Simulate Surgical Interventions for Deep Veins
Published on: May 24, 2024
Related Concept Videos
01:28Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
01:24Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
01:11Overview of Systemic Veins
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
01:28Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
01:24Esophageal Varices-I: Introduction