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Multiple brain abscesses in a neonate: a rare case report along with review of literature

Aanand Mehta1, Manish Yadav2, Bishal K Gupta2

  • 1Tribhuvan University Teaching Hospital, Maharajgunj.

Annals of Medicine and Surgery (2012)
|August 9, 2024
PubMed
Abstract

Insights

Multiple brain abscesses caused by Candida albicans are rare in neonates. Early diagnosis and treatment are crucial for reducing mortality in these challenging fungal infections.

Area of Science:

  • Neonatal neurology
  • Infectious diseases
  • Mycology

Background:

  • Brain abscess (BA) is a serious pyogenic infection of brain tissue.
  • Multiple BAs are uncommon in neonates, with fungal causes being exceptionally rare.
  • Untreated BAs have high mortality rates.

Observation:

  • A 20-day-old neonate presented with fever, decreased activity, jaundice, and seizures.
  • Imaging revealed multiple cerebral abscesses.
  • Candida albicans was identified as the causative agent after pus culture.

Findings:

  • The neonate underwent USG-guided drainage and a 6-week antifungal therapy.
  • Successful treatment of a rare fungal brain abscess in a neonate was achieved.
  • This case underscores the challenge of diagnosing fungal BAs that mimic bacterial infections.

Implications:

  • Highlights the critical need to consider fungal etiologies in neonatal brain abscesses.
  • Emphasizes the importance of early diagnosis and prompt management for improved outcomes.
  • Demonstrates the successful treatment of a rare Candida albicans brain abscess in a neonate.
Keywords:
brain abscessescandida abscessescandida brain abscessmultiple cerebral abscessneonates

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