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ZEBRA study: The Z stitch Early Bed Rest Assessment study
Adarsh Katamreddy1, Ryle Przybylowicz1, Jose Lozano Garcia1
1Division of Cardiology, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon.
Heart Rhythm O2
|August 9, 2024
Summary
Early mobilization after Z-stitch venous access in electrophysiology procedures may improve patient satisfaction without compromising safety. The ZEBRA study assesses early ambulation benefits versus prolonged bed rest.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Patient Safety
Background:
- Venous vascular access management is crucial for electrophysiology (EP) procedures.
- The Z-stitch method offers effective venous hemostasis.
- Prolonged bed rest post-procedure can negatively impact patient satisfaction.
Purpose of the Study:
- To evaluate if early mobilization after Z-stitch placement enhances patient satisfaction.
- To assess the safety of early mobilization compared to standard prolonged bed rest.
- To quantify patient satisfaction metrics and safety parameters in EP procedures.
Main Methods:
- Prospective, multicenter, randomized clinical trial of approximately 200 patients.
- Random assignment to 1-hour or 4-hour bed rest post-Z-stitch.
- Assessment of patient satisfaction via survey and monitoring of safety endpoints like hematomas and bleeding.
Main Results:
- Anticipated higher patient satisfaction scores with early mobilization.
- Close monitoring of hematomas, pain medication use, and healthcare costs.
- Evaluation of 30-day patient outcomes, including ambulation time and groin complication-related visits.
Conclusions:
- The ZEBRA study addresses a gap in post-EP procedure care knowledge.
- Findings could influence future guidelines for venous vascular access management.
- Early mobilization may improve patient experience and outcomes in EP procedures.
