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Outcomes of ST-Elevation Myocardial Infarction in Patients With Opioid Dependence: A National Inpatient Sample Study
Abdel-Rhman Mohamed1, Ahmad Abdelrahman1, Momin Shah1
1Internal Medicine, The University of Toledo Medical Center, Toledo, USA.
Cureus
|August 9, 2024
Summary
Opioid dependence did not significantly impact inpatient mortality or hospitalization costs for ST-segment elevation myocardial infarction (STEMI) patients. However, opioid-dependent STEMI patients experienced a longer hospital stay, highlighting a need for further research.
Area of Science:
- Cardiology
- Pharmacology
- Public Health
Background:
- ST-segment elevation myocardial infarction (STEMI) requires prompt intervention to preserve cardiac function.
- Opioids are commonly used for STEMI-related chest pain but may have adverse effects.
- The impact of opioid dependence on STEMI patient outcomes is not fully understood.
Purpose of the Study:
- To evaluate the effect of opioid dependence on inpatient mortality, length of hospitalization, and hospitalization costs in STEMI patients.
- To identify comorbidities and demographic factors associated with opioid dependence in STEMI patients.
Main Methods:
- Large nationwide retrospective observational study using 2019 National Inpatient Sample (NIS) data.
- Identified STEMI patients (ICD-10 codes) with and without opioid dependence.
- Utilized multivariable logistic and linear regression models, adjusting for numerous confounders.
Main Results:
- Opioid-dependent STEMI patients were younger, had lower income, higher rates of substance use, and more chronic lung disease.
- Inpatient mortality and hospitalization costs were not significantly different between opioid-dependent and non-dependent STEMI patients.
- Opioid dependence was associated with a significantly longer length of hospitalization in STEMI patients.
Conclusions:
- Opioid dependence does not significantly affect inpatient mortality or cost of hospitalization for STEMI patients.
- Opioid dependence is linked to an increased length of hospital stay for STEMI patients.
- Further investigation into the effects of opioid dependence on hospitalization duration in STEMI is warranted.
Keywords:
cad: coronary artery diseaseillicit drug usenational inpatient sample (nis) and the healthcare cost and utilization project (hcup)opiate misusest-elevation myocardial infarction (stemi)More Related Videos
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