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Updated: Jun 17, 2025

Analysis of Termination of Transcription Using BrUTP-strand-specific Transcription Run-on TRO Approach
Published on: March 12, 2017
Transcriptional bursting: from fundamentals to novel insights
Daniel Hebenstreit1, Pradip Karmakar1
1School of Life Sciences, University of Warwick, CV4 7AL Coventry, U.K.
Abstract:
Transcription occurs as irregular bursts in a very wide range of systems, including numerous different species and many genes within these. In this review, we examine the underlying theories, discuss how these relate to experimental measurements, and explore some of the discrepancies that have emerged among various studies. Finally, we consider more recent works that integrate novel concepts, such as the involvement of biomolecular condensates in enhancer-promoter interactions and their effects on the dynamics of transcriptional bursting.
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