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Updated: Jun 17, 2025
Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
Untreated pulmonary sequestration with recurrent superinfection -supporting COPD development in a 42 year old male
Maximilian Leitner1, Jeannine L Kühnle1, Petra Ecker2
1Dept. of Internal Medicine V - Pneumology, Allergology, and Intensive Care Medicine; University Hospital and University of Saarland, Homburg, Germany.
Background:
Pulmonary sequestration is a congenital malformation in which nonfunctional lung tissue develops without connection to the bronchial system. The main complication is the occurrence of recurrent pneumonia.
Case Presentation:
We describe the case of a patient who was incidentally diagnosed with PS as part of the diagnostic algorithm for community-acquired pneumonia. Due to the relatively late diagnosis, the recurrent bronchopulmonary was conducive to the development of COPD and pulmonary emphysema. For prognostic reasons, surgical resection was performed by posterolateral thoracotomy.
Conclusions:
Although cigarette smoking is the main risk factor for developing COPD, recurring lung infections may have a synergistic effect. Sometimes recurrent infections are caused by a congenital malformation. Especially in adults who have had recurrent pneumonia since childhood.
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