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Updated: Jun 17, 2025

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
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Globoside Is an Essential Intracellular Factor Required for Parvovirus B19 Endosomal Escape

Jan Bieri1, Corinne Suter1,2, Oliver Caliaro1,2

  • 1Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Freiestrasse 3, 3012 Bern, Switzerland.

Cells
|August 9, 2024
PubMed
Summary

Human parvovirus B19 (B19V) entry does not disrupt endosomes. Instead, globoside facilitates B19V escape via the Golgi, challenging previous models of viral entry.

Keywords:
B19Vendosomal escapeglobosideparvovirus B19phospholipase A2virus entry

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