Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hormonal abnormalities in renal transplantation.

V Bonomini, C Campieri, C Feletti

    Contributions to Nephrology
    |January 1, 1985
    PubMed
    Summary

    Endocrine disorders often persist after kidney transplants, with only two-thirds of patients seeing full recovery. Remaining abnormalities, like hyperparathyroidism and sexual dysfunction, require ongoing management for better patient and graft outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Family recurrence and oligo-anuria predict uremic restless legs syndrome.

    Acta neurologica Scandinavica·2011
    Same author

    On a case of kidney hypernephroma evolved between the pages of the transverse mesocolon.

    Urologia·2010
    Same author

    Early and delayed orthotic treatment in congenital metatarsus varus: effectiveness of two types of orthoses.

    Europa medicophysica·2005
    Same author

    [Therapy strategies in the prevention of chronic allograft nephropathy].

    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2005
    Same author

    Tacrolimus-associated myositis: a case report in a renal transplant patient.

    Transplantation proceedings·2004
    Same author

    Bionic kidney.

    Artificial cells, blood substitutes, and immobilization biotechnology·2003

    Area of Science:

    • Nephrology
    • Endocrinology
    • Transplantation Medicine

    Background:

    • Uremia and dialysis are associated with numerous endocrine disorders.
    • Kidney transplantation is expected to resolve these hormonal imbalances.
    • Persistence of endocrine dysfunction post-transplant impacts patient health.

    Purpose of the Study:

    • To evaluate the long-term resolution of endocrine disorders after renal transplantation.
    • To identify the types and origins of persistent endocrine abnormalities.
    • To understand the clinical significance of these abnormalities for prognosis.

    Main Methods:

    • Retrospective analysis of 71 out of 275 renal transplant recipients.
    • Serial studies with regular clinical and laboratory checks.

    Related Experiment Videos

  • Documentation of various endocrine abnormalities and graft function.

    • Main Results:

    • Only approximately two-thirds of successfully transplanted patients experience complete resolution of endocrine disorders.
    • Persistent abnormalities include those 'inherited' from uremia (e.g., hyperparathyroidism), steroid-related (e.g., hyperinsulinism), and de novo conditions (e.g., erythrocytosis).
    • These abnormalities can occur with varying graft function, presentation, and outcomes.

    Conclusions:

    • Endocrine disorders frequently persist after renal transplantation, challenging the assumption of complete resolution.
    • Understanding and managing these persistent abnormalities is crucial for long-term patient and graft survival.
    • Further research is needed to elucidate the mechanisms and optimize treatment for post-transplant endocrine dysfunction.