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Updated: Apr 10, 2026

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
Published on: June 9, 2018
How are segmentation and binding computed and represented in the brain?
Christoph von der Malsburg1,2,3
1Frankfurt Institute for Advanced Studies, Ruth-Moufang-Str. 1, 60476, Frankfurt, Germany. malsburg@fias.uni-frankfurt.de.
Abstract:
A programmatically described solution to the segmentation problem is taken as opportunity to dicuss the neural architecture problem of vision. At the center of this problem is the formation of holistic entities (the Gestalt phenomenon) out of masses of neurons (the binding problem). As formulated in the Dynamic Net Architecture (DNA), neurons can become part of a (short-term) stable state only if supported inside a coherent network ('net'). Integration into nets is the basis for global treatment of structures, such as recognition as rigid body or projection to an invariant model.
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