Related Experiment Video

Updated: Jun 17, 2025

A High-content Assay for Monitoring AMPA Receptor Trafficking
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Non-canonical function of ADAM10 in presynaptic plasticity

Julia Bär1,2, Tomas Fanutza1,2, Christopher C Reimann2

  • 1AG Optobiology, Institute of Biology, Humboldt Universität Zu Berlin, 10115, Berlin, Germany.

Cellular and Molecular Life Sciences : CMLS
|August 9, 2024
PubMed
Summary

Disintegrin And Metalloproteinase 10 (ADAM10) is crucial for neuronal development. This study reveals ADAM10’s role in regulating synaptic vesicle exocytosis at hippocampal mossy fiber synapses.

Keywords:
CA3Mossy fiber facilitationProteaseShort-term plasticityVesicle release

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