Orthostatic Intolerance in Children With Long COVID Utilizing a 10-Minute Passive Standing Test

Amanda K Morrow1,2, Cindy Villatoro2, Christina Kokorelis1,2

  • 1Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Clinical Pediatrics
|August 10, 2024
PubMed

Insights

Orthostatic intolerance (OI) is common in children with long COVID, affecting over 70% of those studied. Early screening and treatment for OI are crucial for pediatric long COVID patients.

Area of Science:

  • Pediatric medicine
  • Cardiology
  • Infectious diseases

Background:

  • Long COVID presents diverse symptoms in children, with orthostatic intolerance (OI) increasingly recognized.
  • OI can significantly impact daily activities and quality of life in pediatric populations.

Purpose of the Study:

  • To determine the prevalence of OI in children diagnosed with long COVID.
  • To identify specific types of orthostatic conditions present in this cohort.

Main Methods:

  • A cohort of 92 children with long COVID was evaluated.
  • A bedside passive standing test was administered in a specialized pediatric post-COVID-19 rehabilitation clinic.
  • Diagnostic criteria for various orthostatic conditions were applied.

Main Results:

  • A high prevalence of OI was observed, with 71% of participants meeting criteria for an orthostatic condition.
  • Identified conditions included postural orthostatic tachycardia syndrome (POTS), orthostatic tachycardia (OT), classic orthostatic hypotension (OH), delayed OH, and orthostatic hypertension.
  • OI significantly impacts pediatric long COVID patients.

Conclusions:

  • Orthostatic intolerance is a frequent complication of pediatric long COVID.
  • Routine clinical screening for OI is recommended for children with long COVID.
  • Timely management strategies are essential for improving outcomes in affected children.