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The Engineered Drug 3'UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic

Chidiebere U Awah1,2, Joo Sun Mun3, Aloka Paragodaarachchi3,4

  • 1Department of Biological Sciences, Hunter College, City University of New York, New York, NY 10065, USA.

Cancers
|August 10, 2024
PubMed

Keywords:
c-MYC-STAT5A/5B-PD-L1 complexdestabilized 3′UTR (AU-rich elements)iron oxide nanocage (IO)mRNA poly U stabilizing elementsnonsense-mediated decay (NMD)triple-negative breast cancer (TNBC)

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