Jove
Visualize
Contact Us

Related Experiment Videos

Flexor tendon healing.

P R Manske, R H Gelberman, P A Lesker

    Hand Clinics
    |February 1, 1985
    PubMed
    Summary

    Flexor tendon healing involves both external and internal cells. While peripheral adhesions often accompany healing, they are not essential for successful tendon repair.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of ice on pain after corticosteroid injection in the hand and wrist: a randomized controlled trial.

    The Journal of hand surgery, European volume·2016
    Same author

    Unreduced isolated radial head dislocation in a child: a case report.

    Orthopedics·2014
    Same author

    Distal radioulnar joint subluxation secondary to excision of the radial head.

    Orthopedics·2014
    Same author

    Peripheral nerve compression: etiology, critical pressure threshold, and clinical assessment.

    Orthopedics·2014
    Same author

    Controlled delivery of mesenchymal stem cells and growth factors using a nanofiber scaffold for tendon repair.

    Acta biomaterialia·2013
    Same author

    Incidence of re-operation and subjective outcome following in situ decompression of the ulnar nerve at the cubital tunnel.

    The Journal of hand surgery, European volume·2009
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Orthopedics
    • Regenerative Medicine
    • Biomedical Engineering

    Background:

    • Tendon healing is a complex biological process.
    • Traditionally, flexor tendon repair was thought to rely heavily on extrinsic fibroblasts.
    • The role of intrinsic fibroblasts in tendon repair is an area of ongoing research.

    Purpose of the Study:

    • To investigate the cellular mechanisms of flexor tendon healing.
    • To clarify the necessity of peripheral adhesions in the tendon repair process.

    Main Methods:

    • Review of current literature on tendon healing.
    • Analysis of cellular contributions (extrinsic vs. intrinsic fibroblasts).
    • Evaluation of the role of peripheral adhesions in repair outcomes.

    Main Results:

    • Flexor tendon repair involves both extrinsic peripheral fibroblasts and intrinsic fibroblasts.
    • Peripheral adhesions, while common, are not essential for successful tendon repair.
    • Intrinsic cellular mechanisms play a significant role in tendon healing.

    Conclusions:

    • Tendon healing is a multifactorial process involving both extrinsic and intrinsic cellular sources.
    • Clinical approaches to flexor tendon repair should consider the contribution of intrinsic tendon cells.
    • Future research should focus on optimizing intrinsic healing mechanisms to improve functional outcomes.

    Related Experiment Videos