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Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Reply to Gianluca Giannarini, Antonio Amodeo, Angelo Porreca and Alessandro Crestani's Letter to the Editor Re: Aldo Brassetti, Gabriele Tuderti, Umberto Anceschi, et al. Sutureless Purely Off clamp Robotic Partial Nephrectomy: Evidence from a Randomized Controlled Noninferiority Trial. Eur Urol 2026;15:S0302-2838(26)02139-1.

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Related Experiment Video

Updated: Nov 2, 2025

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
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Renal Function Preservation in Purely Off-Clamp Sutureless Robotic Partial Nephrectomy: Initial Experience and

Antonio Franco1, Sara Riolo1, Giorgia Tema1

  • 1Department of Urology, Sant'Andrea Hospital, La Sapienza University, 00185 Rome, Italy.

Diagnostics (Basel, Switzerland)
|August 10, 2024
PubMed
Summary

Sutureless off-clamp robot-assisted partial nephrectomy (sl-oc RAPN) is a safe and effective procedure for kidney tumors. This technique shows minimal impact on overall kidney function, preserving oncological outcomes with few complications.

Keywords:
RAPNenucleationkidney cancernephron sparing surgeryrobotic surgery

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Area of Science:

  • Urology
  • Surgical Oncology
  • Nephrology

Background:

  • Robot-assisted partial nephrectomy (RAPN) is a standard treatment for renal masses.
  • Sutureless off-clamp techniques aim to improve outcomes and reduce complications.
  • Evaluating the impact of sutureless off-clamp RAPN (sl-oc RAPN) on renal function is crucial.

Purpose of the Study:

  • To assess the effectiveness and safety of sl-oc RAPN.
  • To specifically evaluate the impact of sl-oc RAPN on renal function.
  • To analyze oncological outcomes and perioperative complications.

Main Methods:

  • A multicenter study involving 21 patients with renal masses (>2 cm, PADUA score ≤6).
  • Patients underwent sl-oc RAPN.
  • Renal function was assessed preoperatively and at 1 and 3 months post-surgery using creatinine, blood urea nitrogen, and sequential renal scintigraphy.

Main Results:

  • The median patient age was 64 years, with a median tumor diameter of 40 mm.
  • Operative time averaged 90 minutes, with estimated blood loss of 150 mL.
  • A statistically significant median decrease in renal function of 10 mL/min was observed (p < 0.01), with renal scintigraphy showing a median decrease of 12% in the operated kidney.

Conclusions:

  • Sutureless off-clamp robot-assisted partial nephrectomy is a safe procedure.
  • The technique demonstrates a minimal impact on renal function alteration.
  • sl-oc RAPN effectively preserves renal function and achieves optimal oncological outcomes with limited complications.