[Secondary chemotherapy in advanced ovarian cancer--new drugs]

The results of secondary chemotherapy in advanced ovarian carcinoma are reviewed. After treatment with alkylants average rates of remission of 40 to 45% are achieved. The duration of remission is about 5 months. The response after treatment with platin is significantly lower. Furthermore, new drugs are summarized. A new class of agents is not identifiable. Advances are to be expected in platin derivates with lower nephrotoxicity rates.