Related Experiment Video
Updated: Jun 17, 2025

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
Published on: September 9, 2015
Recurrent pyogenic brain abscess in immunocompetent patient by Bacteroides fragilis: A silent cause of concern
Sonu Kumari Agrawal1, Tanu Sagar1, P Sarat Chandra2
1Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Abstract:
Anaerobic bacteria are rare but important cause of otogenic brain abscess. Improved patient management techniques and early clinical and laboratory diagnosis of otogenic infections are necessary to reduce the risk of intracranial complications. Here we present a case of recurrent pyogenic brain abscess caused by Bacteroides fragilis secondary to otitis media.
Insights
Anaerobic bacteria, though rare, can cause serious otogenic brain abscesses. Early diagnosis and improved management of middle ear infections are crucial for preventing severe intracranial complications.
Area of Science:
- Neurology
- Infectious Diseases
- Otolaryngology
Background:
- Otogenic brain abscesses, while infrequent, represent a significant neurological complication of middle ear infections.
- Prompt identification and management of otitis media are essential to mitigate the risk of intracranial spread.
Observation:
- This report details a case of recurrent pyogenic brain abscess.
- The abscess was attributed to Bacteroides fragilis, an anaerobic bacterium.
Findings:
- The brain abscess was secondary to a chronic or untreated otitis media.
- Recurrence of the pyogenic abscess highlights potential challenges in complete eradication.
Implications:
- This case underscores the importance of considering anaerobic bacteria in the differential diagnosis of otogenic brain abscesses.
- Effective management strategies for otitis media may reduce the incidence of severe intracranial complications like brain abscesses.
Related Concept Videos
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

