Appendiceal neoplasms in Saudi Arabia: prevalence and clinicopathological profile
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View abstract on PubMed
Summary
This summary is machine-generated.Appendiceal neoplasms (ANs) are increasingly diagnosed in Saudi Arabia, with low-grade appendiceal mucinous neoplasms (LAMNs) being most common. Pathological examination of the appendix is crucial for accurate AN diagnosis and management.
Area Of Science
- Gastroenterology
- Oncology
- Pathology
Background
- Appendiceal neoplasms (ANs) are rare but increasing globally.
- No significant increase in AN prevalence was noted in the Arabian Gulf States.
- Recent trends show a younger age at diagnosis and female predominance for some AN types.
Purpose Of The Study
- To evaluate the prevalence and clinicopathological characteristics of ANs at a Saudi Arabian institution.
- To compare findings with existing regional and international studies.
- To identify trends in AN diagnosis and presentation within the study population.
Main Methods
- Retrospective cohort study.
- Inclusion of patients who underwent appendectomy with histopathological evaluation from May 2015 to June 2020.
- Data collection included demographics, clinical presentation, surgical details, histopathology, complications, and outcomes.
Main Results
- 25 AN patients identified out of 1110 appendectomies (2.3%).
- Low-grade appendiceal mucinous neoplasms (LAMNs) constituted 72% of cases.
- 5-year overall and disease-free survival rates were 88% and 80%, respectively, with minimal complications.
Conclusions
- Appendiceal neoplasm incidence is rising in Saudi Arabia, particularly LAMNs.
- Histopathological examination of the appendix is essential for diagnosing ANs.
- The study highlights the importance of comprehensive pathological analysis in appendiceal pathology.
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