Related Experiment Video

Updated: Jun 17, 2025

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

3.6K

Cardiogenic shock in the context of acute coronary syndromes in Latin America ("LATIN Shock")

Yanina Castillo Costa1, Flavio Delfino2, Victor Mauro3

  • 1Sociedad Argentina de Cardiología.

Current Problems in Cardiology
|August 11, 2024
PubMed

Insights

Cardiogenic shock (CS) in Latin America has very high in-hospital mortality, exceeding 50%. Despite high rates of reperfusion therapy, clinical outcomes for CS patients remain poor.

Area of Science:

  • Cardiology
  • Intensive Care Medicine
  • Clinical Research

Background:

  • Cardiogenic shock (CS) is a severe complication of myocardial infarction, contributing significantly to mortality.
  • Limited data exists regarding the treatment and outcomes of CS in the Latin American population.

Purpose of the Study:

  • To investigate the clinical profile, management strategies, and in-hospital mortality of patients experiencing CS in Latin America.
  • To establish a baseline understanding of CS care and outcomes in this region.

Main Methods:

  • A prospective, multicenter registry was conducted over 24 months.
  • 278 patients with CS secondary to acute coronary syndromes (ACS) were enrolled from 41 centers across Latin America.

Main Results:

  • The study included 278 patients (70.1% male, median age 66 years).
  • ST-elevation ACS accounted for 74.8% of cases; CS was present on admission in 60%.
  • High rates of revascularization (81.3%) and inotropic support (97.8%) were observed, yet overall in-hospital mortality reached 52.7%.

Conclusions:

  • Despite aggressive treatment including high rates of reperfusion, in-hospital mortality for CS in Latin America remains unacceptably high.
  • Further research is needed to identify strategies to improve outcomes for CS patients in this region.

Keywords:
Acute myocardial infarctionCardiogenic shockRegistry

More Related Videos

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.2K
The Intra-Aortic Balloon Pump06:13

The Intra-Aortic Balloon Pump

Published on: February 5, 2021

21.2K

Related Concept Videos

Blood Pressure Imbalances and Circulatory Shock01:24

Blood Pressure Imbalances and Circulatory Shock

Disorders affecting blood volume, vascular tone, or vascular function can disrupt vascular homeostasis, including conditions like hypertension, hemorrhage, and shock.
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
764
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.2K
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
406
Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
2.5K
Antianginal Drugs: Nitrates and β-Blockers01:16

Antianginal Drugs: Nitrates and β-Blockers

In cardiovascular health, antianginal drugs combat angina pectoris — a condition marked by chest pain owing to diminished blood flow to the heart.
Organic nitrates,  such as nitroglycerin, play a pivotal role. Once metabolized, they liberate nitric oxide, a molecular marvel. Nitric oxide triggers guanylyl cyclase and augments cGMP production. This biochemical cascade orchestrates the relaxation of vascular smooth muscles, ushering in vasodilation and enhancing coronary blood flow....
557