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Updated: Jun 17, 2025
Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Correlation of bone age development with overweight and obesity in 23,305 children from Beijing
Bo Zhou1, Xia Qu1,2, Minjun Li1
1Child Healthcare Center, Children's Hospital, Capital Institute of Pediatrics, Beijing, China.
Insights
Children with overweight and obesity show advanced bone age (BA). Nutritional status significantly impacts BA development, with overweight and obesity identified as key risk factors for advanced BA in children.
Area of Science:
- Pediatric endocrinology
- Growth and development
- Nutritional science
Background:
- Nutritional status significantly influences childhood growth and development.
- Bone age (BA) assessment is crucial for evaluating skeletal maturation.
- Overweight and obesity are prevalent public health concerns in children.
Purpose of the Study:
- To investigate the impact of varying nutritional statuses on bone age (BA) changes in children.
- To analyze the association between body mass index (BMI) and BA progression.
- To determine the risk of advanced BA in children classified as overweight or obese.
Main Methods:
- A cross-sectional study involving 23,305 children from Beijing.
- Overweight and obesity defined using China and World Health Organization growth criteria.
- Statistical analysis performed using R version 4.3.0.
Main Results:
- Under Chinese criteria, significant proportions of overweight and obese boys and girls exhibited advanced or significantly advanced BA.
- Overweight and obesity were identified as significant risk factors for both advanced and significantly advanced BA (P <0.001).
- Girls demonstrated a higher rate of advanced BA compared to boys.
Conclusions:
- Differential nutritional statuses contribute to variations in children's BA development.
- Children with overweight and obesity exhibit increased rates of advanced BA.
- Overweight and obesity are confirmed risk factors for advanced BA in pediatric populations.
Purpose:
The aim of this study was to observe the influence of differential nutritional status on bone age (BA) change according to body mass index (BMI) and analyze the risk of advanced bone age in children with overweight and obesity.
Methods:
In total 23,305 children from Beijing were included in this cross-sectional study. Childhood overweight and obesity were defined according to the China and World Health Organization growth criteria. The data were analyzed by the R coding platform version 4.3.0.
Results:
Under the Chinese criteria, 29%, 15%, and 4% of boys with overweight; 33%, 33%, and 3% of boys with obesity; 39%, 25%, and 2% of girls with overweight; and 37%, 42% and 1% of girls with obesity had advanced, significantly advanced and delayed BA, respectively. After adjustment, overweight (odds ratio, 95% confidence interval, P under the Chinese criteria: 2.52, 2.30-2.75, <0.001 and 4.54, 4.06-5.09, <0.001) and obesity (4.31, 3.85-4.82, <0.001 and 14.01, 12.39-15.85, <0.001) were risk factors for both advanced BA and significantly advanced BA.
Conclusions:
Different nutritional statuses lead to differences in children's BA development. Children with overweight and obesity have higher rates of advanced BA under two growth criteria, and girls have more advances in BA than boys do. Overweight and obesity are risk factors for advanced BA.
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