Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

723
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
723

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Adjuvant Radiotherapy on Recurrence Outcomes in pT2N0 Oral Squamous Cell Carcinoma: A Propensity Score-Matched Survival Analysis.

Head & neck·2026
Same author

Pulmonary mycobacterial spindle cell pseudotumour: Report of a case and systematic review of literature.

Lung India : official organ of Indian Chest Society·2026
Same author

Clinicopathologic Characterization of Muscle Biopsy Findings in Overlap Myositis: A Single Tertiary Care Center Experience.

Immunity, inflammation and disease·2026
Same author

The voice of injury: a case report of isolated trauma to the larynx.

Journal of trauma and injury·2026
Same author

Tocilizumab in Refractory Neuro Myelitis Optica Spectrum Disorder and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease - Experience from a Tertiary Care Centre.

Annals of Indian Academy of Neurology·2025
Same author

Neuropathology practice in India: a survey of the current status of diagnostics and training in tertiary care centres.

Pathology·2025

Related Experiment Video

Updated: Jun 17, 2025

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

25.6K

Isolated Mediastinal Goitre: A Case Report.

Sandeep Vajja1, Abhilash Konkimalla1, Sujata Patnaik2

  • 1Department of Surgical Oncology, Nizams Institute of Medical Sciences, 4th floor, Specialty Block, Hyderabad, 500082 Telangana India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|August 12, 2024
PubMed
Summary

Retrosternal goiters, often neglected, can present uniquely after prior thyroid surgery. This case highlights isolated mediastinal goiter requiring a combined cervical and sternotomy approach for successful excision.

Keywords:
Primary mediastinal goitreRetrosternal goitreRevision thyroid surgerySternotomy

More Related Videos

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

502
Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach
05:10

Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach

Published on: September 15, 2023

925

Related Experiment Videos

Last Updated: Jun 17, 2025

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

25.6K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

502
Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach
05:10

Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach

Published on: September 15, 2023

925

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Radiology

Background:

  • Retrosternal goiters are relatively common, often resulting from factors like delayed diagnosis, fear of surgery, or incomplete thyroidectomies.
  • Presentation can be atypical, particularly in patients with a history of thyroid surgery.

Purpose of the Study:

  • To report a rare case of isolated mediastinal goiter (Type 3) in a patient with a history of thyroid surgery.
  • To emphasize the importance of computed tomography (CT) imaging and grading in diagnosing and planning treatment for retrosternal goiters.
  • To discuss the surgical approach for managing mediastinal goiter with potential cervical and mediastinal components.

Main Methods:

  • A 53-year-old female with a history of thyroid surgery presented with a large neck swelling.
  • Computed tomography (CT) imaging revealed an isolated mediastinal goiter (Type 3) without connection to the cervical thyroid.
  • The patient underwent total thyroidectomy and mediastinal goiter excision using a combined cervical and median sternotomy approach.

Main Results:

  • Postoperative histopathology confirmed a benign adenomatous goiter.
  • CT imaging was crucial for identifying the extent and type of the retrosternal goiter.
  • The surgical intervention via cervical and sternotomy approach was successful in excising the mediastinal goiter.

Conclusions:

  • CT imaging and appropriate grading are essential for evaluating retrosternal goiters.
  • Mediastinal extension or seeding of thyroid goiter can occur, especially after previous thyroid surgery.
  • Extra-cervical surgical approaches, such as sternotomy, are recommended for managing primary mediastinal goiters.