Related Experiment Video
Updated: Jun 17, 2025
Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
Performance of Impulse Oscillometry in Identifying Restrictive Lung Defects in a Veteran Cohort
Danielle R Glick1,2, Clayton H Brown3, Lan Li3
1Division of Pulmonary and Critical Care Medicine, School of Medicine, University of Maryland, Baltimore, MD, United States.
Background:
Impulse oscillometry (IOs) is a technique used to evaluate lung function that uses sound waves imposed over tidal breathing to characterize the airways and lung parenchyma. IOs has been particularly useful in the identification of obstructive lung defects. The present analysis seeks to explore the use of IOs in the identification of restrictive lung physiology among a group of Gulf War I veterans exposed to depleted uranium (DU).
Methods:
A total of 36 out of a dynamic 85-veteran cohort attended in-person surveillance visits in 2019 and completed both IOs and PFTs. Performance on IOs was evaluated in a cross-sectional analysis of the group overall and in those identified as having restrictive lung defects defined by either spirometry (FEV1/FVC ≥ LLN and FVC < LLN) or lung volumes (TLC < LLN).
Results:
A total of 6 individuals were identified as having restriction (4 based on spirometry alone and an additional 2 by lung volumes). When restriction was present, IOs values of both resistance and reactance were significantly more abnormal.
Conclusion:
In the assessment of lung function, IOs may be advantageous over PFTs because it is faster to perform and effort-independent. Although little is known about the utility of IOs in identifying restrictive lung physiology, our results support its use.
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