Related Experiment Video
Updated: Jun 17, 2025

A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice
Published on: May 11, 2022
Lip-Lick Cheilitis and Its Connection to the Brain
Riley J Stone1, Gianna M Labert2, Robert A Norman3
1Anthropology, University of South Florida, Tampa, USA.
Abstract:
An eight-year-old male who habitually licked his lips and presented with dry, flaky, and red skin bordering the outside of his lips was diagnosed with lip-lick cheilitis. This condition is exacerbated or, at times, caused by chronic lip-licking, leading to irritation and discomfort. Treatment included tacrolimus 0.03% topical ointment, which he was instructed to apply twice daily. He was also advised to stop licking his lips, maintain proper hydration, and use a stress ball when tempted to lick the irritated region. Following these interventions, there was a clear reduction in both irritation and redness. This condition frequently reflects psychocutaneous interactions, commonly observed in patients with underlying psychological stress, displaying the connection between the brain and skin.
Related Concept Videos
Language and Cognition
Functional Brain Systems: Limbic System
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Ligand-gated Ion Channels
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that...

