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Updated: Jun 17, 2025

Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation
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A Chicken-and-Egg Predicament: Malignant Hypertension Versus HIV-Induced Thrombotic Microangiopathic Anemia Conundrum

Daniel Zamanian1, Akshat Agrawal2, Arpita Pawa1

  • 1Internal Medicine, Willis Knighton Healthcare System, Shreveport, USA.

Cureus
|August 12, 2024
PubMed

Thrombotic microangiopathy (TMA) is a condition characterized by hemolytic anemia, thrombocytopenia, and organ damage due to the formation of microthrombi. It can be classified as primary or secondary, with secondary TMA being associated with conditions such as infections, autoimmune diseases, and malignancies. This report details the case of a 39-year-old male with secondary TMA, exploring the potential roles of malignant hypertension and HIV infection with the aim of examining the potential link between malignant hypertension and HIV infection in the development of TMA, highlighting the need for a thorough and broad diagnostic approach.

Keywords:
end-stage renal failureendothelial damagehuman immunodeficiency virus (hiv)-positivesevere hypertensionthrombotic microangiopathy (tma)

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