The Potential Effects of Diffuse Scleroderma in a Patient With Cervical Kyphosis

Area of Science:

• Rheumatology and Immunology
• Orthopedic Surgery
• Autoimmune Diseases

Background:

• Scleroderma is a complex autoimmune disorder characterized by vascular abnormalities, autoimmunity, and tissue fibrosis.
• The precise etiology of scleroderma remains unclear, but it can manifest with diverse systemic symptoms.
• Rarely, scleroderma impacts cervical spine anatomy through autoimmune processes or calcinosis.

Observation:

• A 60-year-old female with a four-month history of scleroderma presented with significant symptoms.
• The patient exhibited cervical kyphosis, neck pain, impaired ambulation, dysphagia, and edema.
• A reduced range of motion in the neck was also noted.

Findings:

• The case illustrates a rare instance of scleroderma-induced cervical spine alteration.
• Symptoms suggest a potential link between scleroderma pathogenesis and cervical spine structural changes.
• Autoimmune phenomena or dystrophic calcinosis may mediate these cervical spine effects.

Implications:

• This case underscores the importance of considering cervical spine involvement in scleroderma patients.
• Early recognition of spinal complications can guide timely and appropriate management strategies.
• Further research is warranted to elucidate the mechanisms linking scleroderma to cervical spine pathology.