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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Acute Pain Transfusion Reaction: A Case Report.

Purshotam Paudel1, Pammy Sinha2

  • 1Transfusion Medicine, Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry, IND.

Cureus
|August 12, 2024
PubMed
Summary

Acute pain transfusion reactions (APTR) are sudden, severe joint pain after blood transfusions. These reactions, involving packed red blood cells or fresh frozen plasma, are usually self-limited and managed with supportive care.

Keywords:
acute pain transfusion reactioncytokinespacked red blood cells ( prbc)paintransfusion reaction

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Area of Science:

  • Transfusion Medicine
  • Hematology
  • Patient Safety

Background:

  • Transfusion-related adverse events are common with packed red blood cells (PRBCs) and fresh frozen plasma (FFP).
  • Acute Pain Transfusion Reaction (APTR) is a specific type of reaction characterized by sudden, intense joint pain post-transfusion.

Observation:

  • Two cases are presented: a 38-year-old female receiving PRBCs and a 69-year-old female receiving FFP.
  • Both patients developed acute, severe pain during or shortly after their respective transfusions, with no significant vital sign changes or other identified causes.

Findings:

  • Both patients were diagnosed with acute pain transfusion reactions (APTR).
  • APTR management in these cases involved symptomatic treatment, including pain control and emotional support.

Implications:

  • APTR is a distinct transfusion reaction that requires prompt recognition and management.
  • Supportive care is often sufficient for resolving APTR symptoms, highlighting the importance of monitoring patients during and after blood product administration.