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Published on: August 26, 2014
Increased Colonic Fluorodeoxyglucose Uptake in Melanosis Coli-A Case Series of Three Patients
Ryo Katsumata1, Noriaki Manabe2, Maki Ayaki2
1Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center, Okayama, Japan.
Abstract:
We report 3 Japanese cases with increased colonic 18-fluorodeoxyglucose (FDG) uptake in association with melanosis coli. Case 1: A 56-year-old woman received 18-FDG positron emission tomography (PET) for comprehensive medical checkup. Case 2: A 79-year-old man received FDG-PET for follow-up evaluation for intestinal cancer. Case 3: A 51-year-old woman received FDG-PET for medical checkup. Each showed increased cecal and/or ascending colonic uptake without any colonic wall changes. Colonoscopy detected melanosis coli where FDG uptake was demonstrably increased. Neither malignancy nor inflammatory response was confirmed. Succeeding follow-ups showed neither malignant nor inflammatory lesions in any of the patients.

