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Endoscopic Ultrasound-Guided Liver Biopsy in Clinical Practice
Avik Sarkar1, Peter Dellatore1, Abhishek Bhurwal1
1Division of Gastroenterology and Hepatology, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Gastro Hep Advances
|August 12, 2024
Summary
Endoscopic ultrasound (EUS)-guided liver biopsy is a safe and effective new method for obtaining liver tissue samples. This technique ensures adequate tissue for analysis and avoids sampling errors, offering a viable alternative to traditional biopsies.
Area of Science:
- Gastroenterology
- Hepatology
- Interventional Endoscopy
Background:
- Traditional liver biopsy methods include percutaneous, transjugular, and surgical approaches.
- Endoscopic ultrasound (EUS)-guided liver biopsy is an emerging technique for liver parenchyma sampling.
- Limited data exist on the adequacy of tissue samples obtained via EUS-guided liver biopsy for histological analysis.
Purpose of the Study:
- To evaluate the efficacy and safety of EUS-guided liver biopsy.
- To assess the adequacy of tissue samples obtained through EUS-guided liver biopsy for histopathological examination.
- To review the experience of two major tertiary care centers regarding EUS-guided liver biopsy.
Main Methods:
- Retrospective study of patients undergoing EUS-guided liver biopsy from March 2018 to October 2019.
- Inclusion of all patients from two tertiary care centers.
- Assessment of technical success, specimen details (length, portal tracts), and adverse events.
Main Results:
- 100% technical success rate in 229 patients.
- 98.7% of patients (226/229) yielded adequate tissue for histopathology (mean length 3.20 cm, mean 20.2 complete portal tracts).
- An overall adverse event rate of 2.6% was observed.
Conclusions:
- EUS-guided liver biopsy provides sufficient tissue for histological analysis.
- This method is a safe and effective alternative to conventional liver biopsy techniques.
- The study demonstrates the clinical utility of EUS-guided liver biopsy in large tertiary care settings.
