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Updated: Jun 17, 2025

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

Published on: March 29, 2019

Non-Muscle Invasive Bladder Cancer: Many More Patients Die With It Than Of It.

Kathryn McGonagle^1,2, Ellen J Dematt³, Zhibao Mi³

¹Geisel School of Medicine at Dartmouth, Hanover, NH, USA.

Bladder Cancer (Amsterdam, Netherlands)

|August 12, 2024

Summary

This summary is machine-generated.

Survival for non-muscle invasive bladder cancer (NMIBC) patients is high, with 5-year specific survival at 93%. However, overall survival is lower (68%) due to comorbidities, suggesting a need to re-evaluate surveillance intensity for NMIBC.

Keywords:

Non-muscle invasive bladder cancer cancer surveillance cancer-specific survival cystoscopy overall survival

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Area of Science:

Urology
Oncology
Public Health

Background:

Limited data exists for non-muscle invasive bladder cancer (NMIBC) survival.
National Cancer Institute SEER Program data covers all bladder cancers, not specifically NMIBC.

Purpose of the Study:

To determine 5-year overall and bladder cancer-specific survival rates.
Focus on a cohort of Department of Veterans Affairs (VA) patients with NMIBC.

Main Methods:

Identified VA patients with NMIBC undergoing transurethral resection (2003-2013).
Collected demographic, comorbidity, and mortality data.
Calculated survival estimates using Kaplan-Meier methods.

Main Results:

27,008 patients included; median age 69, 99% male.
High comorbidity burden: median score 4, prevalent conditions include COPD, other cancers, diabetes.
5-year overall survival: 68%; 5-year bladder cancer-specific survival: 93%.

Conclusions:

Bladder cancer-specific survival for NMIBC is significantly higher than overall survival.
Comorbidities likely impact overall survival in this veteran population.
Further research is needed on the intensity of surveillance for NMIBC patients.