Presentation and management of marantic endocarditis: A case series

Area of Science:

• Cardiology
• Pathology
• Internal Medicine

Background:

• Marantic endocarditis is a rare form of sterile endocarditis.
• It is infrequently encountered in clinical practice, posing diagnostic and therapeutic challenges.

Observation:

• This case series details five patients diagnosed with marantic endocarditis.
• Diagnosis was confirmed using trans thoracic echocardiography and transesophageal echocardiography.
• Patient conditions included antiphospholipid syndrome (three cases) and advanced malignancy (two cases).

Findings:

• Two patients responded successfully to anticoagulation therapy.
• Two patients required surgical intervention for valvular issues.
• One patient experienced a fatal outcome.

Implications:

• The observed treatment courses align with patterns previously reported in medical literature.
• This case series highlights the variable clinical presentations and management strategies for marantic endocarditis.
• Further research may elucidate optimal therapeutic approaches for this rare condition.