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Updated: Aug 7, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
The impact of His bundle location and direction on the efficacy and safety of ablation
Bangjiaxin Ren1, Ying Cao1, Jing Li1,2
1Department of Cardiology, West China Hospital, Sichuan University, Chengdu, P.R. China.
Insights
The distance between the His bundle and ablation target (DHIS-ABL) impacts supraventricular tachycardia recurrence. Shorter distances increase recurrence risk, but the effect on atrioventricular block risk requires further investigation.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Imaging
Background:
- The relationship between His bundle location, ablation site distance, and ablation outcomes is not well understood.
- Factors influencing His bundle location, such as age, height, and BMI, are relevant to ablation procedures.
Purpose of the Study:
- To investigate the correlation between patient demographics and His bundle location.
- To determine if the distance between the His bundle and ablation target (DHIS-ABL) influences ablation efficacy and complication rates in patients with atrioventricular re-entrant tachycardia (AVNRT) and atrioventricular tachycardia (AVRT).
Main Methods:
- Retrospective analysis of 346 AVNRT and 96 AVRT patients.
- Measurement of His bundle height (HHIS), distance to coronary sinus ostium (DHis-CS), and DHIS-ABL.
- Assessment of recurrence and complications via electrocardiograms 3 months post-ablation.
Main Results:
- His bundle height (HHIS) negatively correlated with age. DHIS-ABL correlated with age, height, and BMI in AVNRT patients, but not in AVRT patients.
- Recurrence rates were 0.9% for AVNRT and 8.7% for AVRT.
- A DHIS-ABL ≤ 10 mm was associated with a higher recurrence rate (p = .013); third-degree atrioventricular block (AVB) incidence was 0.2%.
Conclusions:
- His bundle height correlates with age. DHIS-ABL is influenced by patient demographics in AVNRT.
- Shorter DHIS-ABL is linked to increased supraventricular tachycardia recurrence.
- Further research with larger cohorts is needed to clarify the impact of DHIS-ABL on AVB risk.
Background:
The impact of the His bundle location and distance from the ablation site on ablation efficacy and complication risk remains unexplored. We determined the correlation between age, height, body mass index (BMI), and the His bundle location, and whether the distance between the His bundle and ablation target (DHIS-ABL) affects ablation safety and efficacy.
Methods:
Overall, 346 patients with atrioventricular nodal re-entrant tachycardia (AVNRT) and 96 with atrioventricular re-entrant tachycardia (AVRT) were retrospectively analyzed. The distance between the His bundle and the coronary sinus ostium (DHis-CS), the height of the His bundle (HHIS), and DHIS-ABL were measured. Electrocardiograms were obtained 3 months post-ablation to assess recurrence and complications.
Results:
Multiple linear regression showed that HHIS was negatively correlated with age in both groups. In AVNRT patients, DHIS-ABL was associated with age, height, and BMI; DHIS-CS was only negatively correlated with age. In AVRT patients, there was no significant correlation between the DHIS-ABL and age, height, or BMI. The recurrence rates in the AVNRT and AVRT groups were 0.9% and 8.7%, respectively. Subgroup analysis showed that patients with DHIS-ABL ≤ 10 mm had a higher recurrence rate than those with DHIS-ABL > 10 mm (p = .013). The incidence of third-degree atrioventricular block (AVB) complications was 0.2%.
Conclusions:
HHIS was negatively correlated with age but not with height and BMI. The DHIS-ABL correlated with age, height, and BMI in AVNRT patients. A short DHIS-ABL led to a higher rate of supraventricular tachycardia recurrence; whether this affects AVB risk warrants further studies with larger sample sizes.
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