A Hand-Foot-and-Mouth Disease Outbreak in an Atypical Population of College Students

Nancy G Russell1, Roanna Kessler1

  • 1Johns Hopkins University, Baltimore, MD, USA.

Insights

Hand-foot-and-mouth disease (HFMD) is rare in young adults. This report details an unusual CVA6-caused HFMD outbreak among 138 college students, offering insights for clinicians.

Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • Hand-foot-and-mouth disease (HFMD) typically affects pediatric populations.
  • HFMD is infrequently observed in adolescents and young adults.
  • Outbreaks in college settings are uncommon but significant.

Purpose of the Study:

  • To report an atypical outbreak of HFMD in college students.
  • To identify the causative agent and describe clinical presentations.
  • To inform clinicians about HFMD in older adolescent and young adult populations.

Main Methods:

  • Retrospective case review of HFMD cases among university students.
  • Epidemiological data collection from August to November 2018.
  • Laboratory testing of samples to identify the viral strain.

Main Results:

  • 138 qualifying cases of HFMD were identified.
  • All tested samples were positive for Coxsackievirus A6 (CVA6).
  • The outbreak occurred in a mid-size university in the mid-Atlantic U.S.

Conclusions:

  • CVA6 can cause significant HFMD outbreaks in college-aged populations.
  • Clinicians should consider HFMD in adolescents and young adults presenting with characteristic symptoms.
  • Understanding atypical HFMD presentations is crucial for effective public health management in university settings.