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[Necrotizing soft tissue infections]
Christian Lanckohr1, Dagmar Horn2, Steffen Roßlenbroich3
1Antibiotic Stewardship (ABS)-Team, Institut für Hygiene, Universitätsklinikum Münster, Robert-Koch-Straße 41, 48149, Münster, Deutschland. Christian.lanckohr@ukmuenster.de.
Die Anaesthesiologie
|August 12, 2024
Summary
Necrotizing soft tissue infections are severe bacterial infections requiring immediate surgical and antimicrobial treatment due to high mortality. Survivors often face long-term functional impairments and require extensive reconstructive surgery.
Area of Science:
- Infectious Diseases
- Surgical Pathology
- Critical Care Medicine
Context:
- Necrotizing soft tissue infections (NSTIs) are severe, rapidly progressing bacterial infections affecting skin, connective tissue, and muscles.
- These infections present as a time-sensitive emergency with high mortality rates, often necessitating intensive care unit admission.
Purpose:
- This review provides a comprehensive overview of necrotizing soft tissue infections.
- It details current knowledge on diagnostics, treatment strategies, and post-treatment care for these complex infections.
Summary:
- NSTIs involve necrotic tissue destruction caused by various bacterial pathogens across the body.
- Essential management includes rapid, radical surgical debridement and timely, adequate antimicrobial therapy.
- Interprofessional collaboration is crucial throughout all disease phases.
Impact:
- Prompt and effective treatment is vital to reduce mortality and minimize severe functional impairments in survivors.
- Extensive soft tissue damage often necessitates significant reconstructive plastic surgery follow-up.
- Understanding NSTI complexities guides improved patient outcomes and rehabilitation.
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