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Updated: Jun 17, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Identification of Dementia & Mild Cognitive Impairment in Chinese Elderly Using Machine Learning
Tong-Tong Ying1, Li-Ying Zhuang1, Shan-Hu Xu1
1Department of Neurology, Zhejiang Hospital, Hangzhou, China.
Objective:
To assess the role of Machine Learning (ML) in identification critical factors of dementia and mild cognitive impairment.
Methods:
371 elderly individuals were ultimately included in the ML analysis. Demographic information (including gender, age, parity, visual acuity, auditory function, mobility, and medication history) and 35 features from 10 assessment scales were used for modeling. Five machine learning classifiers were used for evaluation, employing a procedure involving feature extraction, selection, model training, and performance assessment to identify key indicative factors.
Results:
The Random Forest model, after data preprocessing, Information Gain, and Meta-analysis, utilized three training features and four meta-features, achieving an area under the curve of 0.961 and a accuracy of 0.894, showcasing exceptional accuracy for the identification of dementia and mild cognitive impairment.
Conclusions:
ML serves as a identification tool for dementia and mild cognitive impairment. Using Information Gain and Meta-feature analysis, Clinical Dementia Rating (CDR) and Neuropsychiatric Inventory (NPI) scale information emerged as crucial for training the Random Forest model.
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