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Letter by Soltani-Kermanshahi Regarding Article, "ChaMP-CMD: A Phenotype-Blinded, Randomized Controlled, Cross-Over

Mojtaba Soltani-Kermanshahi1

  • 1Social Determinants of Health Research Center, School of Medicine, Semnan University of Medical Sciences, Iran.

Circulation
|August 12, 2024
PubMed
Abstract

No abstract available in PubMed .

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Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...
Blinding01:11

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Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.