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Updated: Jun 17, 2025

Ferric Chloride-induced Murine Thrombosis Models
Published on: September 5, 2016
GENETIC DETERMINANTS OF THROMBOSIS
1BALTIMORE, MARYLAND.
Abstract:
Venous thromboembolism (VTE) is a major cause of morbidity and mortality in the United States. VTE is caused by genetic and acquired conditions, but the genetic variants that increase the risk of VTE are not fully characterized. Recent genome-wide association studies (GWAS) have discovered novel genetic loci linked to VTE. Some of these loci have been characterized, uncovering new pathways that regulate VTE. Functional characterization of candidate genes discovered by GWAS may reveal new therapeutic targets to treat and prevent abnormal thrombosis or bleeding.
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