Recent progress on field-effect transistor-based biosensors: device perspective

Area of Science:

• Biotechnology
• Electrical Engineering
• Materials Science

Background:

• Field-effect transistor (FET)-based biosensors have emerged as powerful tools for detecting diverse biomolecules.
• Their applications span critical sectors including medical diagnostics, food safety, agriculture, environmental monitoring, and defense.

Purpose of the Study:

• To provide a comprehensive review of recent advancements in FET-based biosensor architectures.
• To offer guidelines for optimizing device dimensions, design, and realization for enhanced performance.
• To highlight future research directions in FET biosensor topology.

Main Methods:

• Literature review of existing FET-based biosensor architectures.
• Analysis of design considerations for improving sensitivity, detection time, and selectivity.
• Exploration of emerging FET biosensor technologies and their potential.

Main Results:

• Identification of key architectural innovations driving FET biosensor performance improvements.
• Establishment of design principles for achieving superior sensitivity and rapid detection.
• Overview of current trends and future potential of FET biosensor technology.

Conclusions:

• FET-based biosensors represent a rapidly evolving field with significant potential across multiple industries.
• Optimized design and architecture are crucial for maximizing biosensor performance.
• Further research into novel topologies promises to unlock new capabilities for FET biosensors.