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Updated: Jun 17, 2025

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
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Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

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Photo-BQCA: Positive Allosteric Modulators Enabling Optical Control of the M1 Receptor

Hubert Gerwe1, Eva Schaller1, Rosalba Sortino2,3,4

  • 1Pharmaceutical and Medicinal Chemistry Institute of Pharmacy and Food Chemistry, Julius Maximilian University of Würzburg (JMU), Am Hubland, 97074, Würzburg, Germany.

Angewandte Chemie (International Ed. in English)
|August 13, 2024
PubMed

Keywords:
GPCRallosterismmuscarinic ligandsphotopharmacologyphotoswitch

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