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Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

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Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
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Related Experiment Video

Updated: Jun 17, 2025

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Incorporating Individual-Level Treatment Effects and Outcome Preferences Into Personalized Blood Pressure Target

Simon B Ascher1,2, Richard L Kravitz2, Rebecca Scherzer1

  • 1Department of Internal Medicine, Kidney Health Research Collaborative San Francisco Veterans Affairs Health Care System and University of California San Francisco San Francisco CA.

Journal of the American Heart Association
|August 13, 2024
PubMed
Summary
This summary is machine-generated.

Tailoring blood pressure (BP) targets using individual patient risks and preferences can refine treatment recommendations. Most participants in the SPRINT trial showed a net benefit favoring intensive BP lowering.

Keywords:
hypertensionpatient preferencesprecision medicinepredictionshared decision‐making

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Area of Science:

  • Cardiovascular Medicine
  • Clinical Trials
  • Health Economics

Background:

  • No established frameworks exist for shared decision-making regarding blood pressure (BP) targets in hypertension.
  • The Systolic Blood Pressure Intervention Trial (SPRINT) provides data that could potentially be personalized.

Purpose of the Study:

  • To determine if SPRINT trial results can be tailored to individual patients.
  • To assess the utility of predicted risks and simulated preferences in guiding BP target selection.

Main Methods:

  • Developed and validated Cox models to predict individual risk differences between intensive and standard BP lowering.
  • Combined individual treatment effects using simulated preference weights to calculate net benefit.
  • Compared net benefits between participants with high and low risk of adverse events (AEs).

Main Results:

  • In simulations weighting cardiovascular events, cognitive impairment, and death more heavily than AEs, 100% of participants showed a net benefit favoring intensive BP lowering (median net benefit: 3.3 percentage points).
  • When benefits and harms were weighted similarly, 87% of participants had a positive net benefit (median net benefit: 0.8 percentage points).
  • Participants at higher risk of AEs still demonstrated a greater net benefit from intensive BP lowering compared to those at lower risk.

Conclusions:

  • A predicted net benefit favoring intensive BP lowering was observed in most SPRINT participants.
  • The magnitude of this net benefit varied significantly among individuals.
  • Personalizing BP target recommendations based on individual risk profiles and preferences is a promising approach.