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Cadaveric renal transplant failure: the short-term sequelae.

G Rodin, K Voshart, D Cattran

    International Journal of Psychiatry in Medicine
    |January 1, 1985
    PubMed
    Summary

    Successful cadaveric transplants significantly improve psychosocial well-being in patients. While graft failure impacts physical activity, it does not negatively affect psychosocial functioning in the short term.

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    Area of Science:

    • Nephrology
    • Transplantation Immunology
    • Quality of Life Research

    Background:

    • Assessing quality of life (QOL) is crucial for patients awaiting organ transplantation.
    • Cadaveric transplantation is a common procedure with known risks and benefits.

    Purpose of the Study:

    • To evaluate the impact of cadaveric transplantation on patient quality of life.
    • To compare QOL outcomes between transplanted and non-transplanted patients on the waiting list.

    Main Methods:

    • Prospective evaluation of 103 patients on a cadaveric transplant waiting list.
    • QOL assessment at baseline, and six months post-transplant or post-waiting list placement.
    • Statistical analysis of mortality, graft failure, physical activity, and psychosocial functioning.

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    Main Results:

    • Sixty-three patients received transplants; 12.7% mortality within six months (not statistically significant vs. non-transplanted).
    • Graft failure rate was 23.6% among surviving transplanted patients.
    • Graft failure correlated with decreased physical activity but not psychosocial function.
    • Successful transplants significantly improved psychosocial well-being, despite no increase in physical activity.

    Conclusions:

    • Cadaveric transplantation can lead to improved quality of life, particularly in psychosocial well-being.
    • A notable graft failure rate (23.6%) persists with cadaveric transplantation.
    • Short-term graft failure does not necessarily lead to a decline in psychosocial functioning.