The predictors of coronary slow flow in patients undergoing coronary angiography

Romi Ermawan1, Yusra Pintaningrum2, Yanna Indrayana2

  • 1Faculty of Medicine, Mataram University, FK UNRAM, Jl. Pendidikan, No. 37, Mataram, NTB, Indonesia. romi@unram.ac.id.

Insights

Coronary slow flow (CSF) is a condition causing ischemic symptoms without artery blockage. Larger coronary artery diameter is a strong predictor of CSF in patients undergoing angiography.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Diagnostic Imaging

Background:

  • Coronary artery disease (CAD) presents challenges in specific populations with ischemic symptoms but no epicardial artery obstruction.
  • This condition is characterized by slow coronary contrast flow, termed coronary slow flow (CSF).

Purpose of the Study:

  • To identify predictors of coronary slow flow (CSF) in patients with ischemic symptoms.
  • To investigate the relationship between coronary artery diameter and CSF.

Main Methods:

  • A case-control study involving 60 subjects (30 with CSF, 30 with normal epicardial coronary artery angiogram - NECA).
  • CSF was defined by a TIMI frame count (TFC) greater than 27 frames.
  • Coronary artery diameter and random blood sugar were assessed as potential predictors.

Main Results:

  • Coronary artery diameter and random blood sugar were significant predictors of CSF.
  • In multivariate analysis, coronary artery diameter remained a significant predictor (adjusted OR 10.08, p < 0.001).
  • An optimal cut-off for coronary artery diameter was >3.56 mm, with 76.7% sensitivity and 70.7% specificity (AUC = 0.787).

Conclusions:

  • Coronary artery diameter is a strong predictor of coronary slow flow (CSF) in patients undergoing coronary angiography.
  • These findings aid in understanding and potentially diagnosing CSF.
Abstract

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