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Association between ischaemic stroke aetiology and leptomeningeal collateral status: a retrospective cohort study

Lina Sojak1, Anna M Toebak1,2,3, Camilla Gallino1

  • 1Department of Neurology and Stroke Center, University Hospital Basel and University of Basel, Basel, Switzerland.

Swiss Medical Weekly
|August 13, 2024
PubMed

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An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
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