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Epilepsy and Seizures: Overview

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

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Updated: Jun 29, 2026

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

Published on: October 2, 2014

Performance validity in a presurgical epilepsy population.

Sofia Lesica^1,2, Hien Luu¹, Michael Lawrence¹

¹Corewell Health, Grand Rapids, MI, USA.

The Clinical Neuropsychologist

|August 14, 2024

Summary

This summary is machine-generated.

Performance validity testing (PVT) failure in epilepsy surgery candidates was linked to poorer cognitive function and higher anxiety, but not demographics or seizure factors. PVT appears reliable for assessing performance validity in this population.

Keywords:

CVLT-II forced choice epilepsy medical symptom validity test reliable digit span test of memory malingering word memory test

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Last Updated: Jun 29, 2026

Performing Behavioral Tasks in Subjects with Intracranial Electrodes

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Published on: October 2, 2014

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy

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Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

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Published on: September 20, 2024

Area of Science:

Neuropsychology
Clinical Neuroscience
Epilepsy Research

Background:

Assessing performance validity is crucial in presurgical epilepsy evaluations.
Understanding factors influencing performance validity can refine diagnostic accuracy.

Purpose of the Study:

To determine the performance validity test (PVT) pass/fail rate in presurgical epilepsy candidates.
To examine associations between performance validity and cognitive performance, mood, and demographic/clinical factors.

Main Methods:

One hundred eighty-three presurgical epilepsy candidates underwent assessment.
A battery including a standalone PVT and two embedded validity measures was administered.

Main Results:

PVT failure (10%) correlated with lower scores across all neurocognitive domains and elevated anxiety.
No significant differences in performance validity were found based on sex, race, age, education, special education history, seizure duration, or medication count.
Significant correlations remained after Bonferroni correction.

Conclusions:

Performance validity testing is a reliable indicator in presurgical epilepsy evaluations.
Demographic and clinical factors do not appear to impact PVT performance in this sample.