Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

X-ray Crystallography

X-ray Crystallography

The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Design, Synthesis and Antitumor Assessment of Phenylureas Bearing 5-Fluoroindolin-2-one Moiety.

Medicinal chemistry (Shariqah (United Arab Emirates))·2020

Same author

Long-term monitoring of PCDD/Fs in soils in the vicinity of a hazardous waste incinerator in China: Temporal variations and environmental impacts.

The Science of the total environment·2020

Same author

Prognostic value of pre-treatment Naples prognostic score (NPS) in patients with osteosarcoma.

World journal of surgical oncology·2020

Same author

Administration of dietary recombinant hepcidin on grass carp (Ctenopharyngodon idella) against Flavobacterium columnare infection under cage aquaculture conditions.

Fish & shellfish immunology·2020

Same author

Honokiol suppresses mycelial growth and reduces virulence of Botrytis cinerea by inducing autophagic activities and apoptosis.

Food microbiology·2020

Same author

Reshaping of pipette tip: A facile and practical strategy for sorbent packing-free solid phase extraction.

Analytica chimica acta·2020

Same journal

Pleural Toxocariasis Presenting as Eosinophilic Pleural Effusion: A Case Report.

Cureus·2026

Same journal

Left Clavicular Pain Following Splenic Rupture After Colonoscopy: A Variant of Kehr's Sign?

Cureus·2026

Same journal

Severe Polyhydramnios Associated With Antenatal Bartter Syndrome.

Cureus·2026

Same journal

Focal Takotsubo Syndrome Mimicking a Distal Coronary Pathology: A Case Report.

Cureus·2026

Same journal

Metachronous Colorectal Carcinomas and Pancreatic Metastasis in Clinically Suspected Lynch Syndrome: An 18-Year Oncologic Course.

Cureus·2026

Same journal

Regional Blocks in the Era of the Opioid Crisis: Evaluating Their Opioid-Sparing Effect.

Cureus·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 17, 2025

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

A Projection Integration Method for X-ray Collimator Design.

¹Research and Development, Zap Surgical Systems, San Carlos, USA.

|August 14, 2024

Summary

This summary is machine-generated.

A new projection integration algorithm quickly optimizes radiation therapy collimator design for stereotactic radiosurgery (SRS). This method accurately models beam profiles, improving dose delivery for small lesions and brain disorders.

Keywords:

beam penumbra collimator small field srs x-ray profile

More Related Videos

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

Related Experiment Videos

Last Updated: Jun 17, 2025

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

Area of Science:

Medical Physics
Radiation Oncology
Biomedical Engineering

Background:

Advancements in radiation therapy, like stereotactic radiosurgery (SRS), demand precise dose delivery.
Accurate placement of small radiation fields is crucial for treating intracranial lesions and brain disorders.

Purpose of the Study:

To introduce a novel numerical concept for designing radiation therapy collimators.
To develop a time-efficient algorithm for generating beam profiles with various collimator apertures and beam spot distributions.

Main Methods:

A projection integration method divides the source beam spot intensity into slices.
Each slice is projected through collimator apertures to the treatment plane, calculating field range and intensity.
The total treatment plane profile is obtained by integrating intensities across all slices.

Main Results:

The algorithm efficiently generates beam profiles for collimator design optimization (penumbra, dose rate, field size).
Generated profiles for a conical pencil beam collimator system were validated against Monte Carlo simulations and measurements.
The method demonstrated effectiveness in optimizing beam characteristics and showed the impact of collimator shape.

Conclusions:

The projection integration method is a fast and informative tool for radiation therapy collimator design.
This validated approach aids in optimizing beam characteristics for precise radiation delivery.
The algorithm is suitable for designing collimators for advanced radiation therapy techniques like SRS.