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Published on: June 29, 2013
Intrauterine Growth References for Turkish Infants
Aytuğ Atıcı1, Arzu Kanık2, Yalçın Çelik1
1Division of Neonatology, Department of Pediatrics, Mersin University School of Medicine, Mersin, Türkiye.
Insights
This study established the first intrauterine growth references for Turkish infants, crucial for accurately assessing fetal development and identifying growth deviations in this population. These new references improve monitoring for Turkish newborns, including those born prematurely.
Area of Science:
- Perinatology
- Pediatric Endocrinology
- Public Health
Background:
- Fetal growth is influenced by ethnic and environmental factors, necessitating region-specific intrauterine growth references.
- Existing growth references may not accurately reflect the development of Turkish infants.
Purpose of the Study:
- To construct comprehensive intrauterine growth references tailored for Turkish infants.
- To provide a reliable tool for monitoring fetal growth and identifying deviations in the Turkish population.
Main Methods:
- A prospective, multicenter, cross-sectional study involving 33 healthcare centers across Türkiye.
- Data collected from 9734 singleton infants born between 24-42 weeks of gestation.
- The Lambda-Mu-Sigma method and penalized likelihood were employed to establish growth curves and percentiles.
Main Results:
- Established intrauterine growth curves and tables specifically for Turkish infants.
- The study analyzed data from 9734 infants, excluding 552 non-compliant cases.
- This represents the first comprehensive reference data for Turkish intrauterine growth.
Conclusions:
- The developed intrauterine growth references are essential for accurate assessment of Turkish infants.
- These references will enhance the follow-up of fetal growth and postnatal growth in premature Turkish infants.
- Improved identification of small for gestational age (SGA) and large for gestational age (LGA) infants is anticipated.
Abstract:
Fetal growth is known to be affected by ethnic and environmental factors; therefore, intrauterine growth references for each community vary and need to be determined individually. This study aimed to construct intrauterine growth references for Turkish infants. This prospective, multicenter, cross-sectional study was performed in collaboration with the Turkish Ministry of Health and the Turkish Neonatology Society, in coordination with Mersin University. The study included 33 healthcare centers from all regions of Türkiye. The study included singleton infants who were born alive at 24-42 weeks of gestation. Weight, length, and head circumference were measured within the first 4 hours of delivery. The Lambda-Mu-Sigma method and penalized likelihood were used to establish the curves and construct percentiles. In all, data from 10 286 infants were analyzed and 552 cases that did not meet the inclusion criteria were excluded. The intrauterine growth curves and tables for Turkish infants were constructed using the data for 9734 singleton infants born at 24-42 weeks of gestation. To the best of our knowledge this is the first study to establish intrauterine growth references for Turkish infants, based on a cohort of infants from all regions of Türkiye. Using these new references, the intrauterine growth of Turkish infants and postnatal growth of those born prematurely can be followed-up more effectively, and it will be possible to more accurately determine if Turkish infants are small for gestational age or large for gestational age.
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