Search research articles

Related Concept Videos

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Technical note: a functional data analysis approach to analyze the light-adapted electroretinogram in children and adolescents.

Documenta ophthalmologica. Advances in ophthalmology·2026

Same author

ERG-Graph: Graph Signal Processing of the Electroretinogram for Classification of Neurodevelopmental Disorders.

Bioengineering (Basel, Switzerland)·2026

Same author

The luminance-response function of the photopic negative response (PhNR): analysing different stimulation, recording and measurement approaches.

Documenta ophthalmologica. Advances in ophthalmology·2026

Same author

Feasibility and reproducibility of handheld and table-mounted optical coherence tomography in children with craniosynostosis.

Eye (London, England)·2026

Same author

Technical note: contour plot visualization of the light adapted electroretinogram using a generalized additive model.

Documenta ophthalmologica. Advances in ophthalmology·2026

Same author

Time Series Classification of Autism Spectrum Disorder Using the Light-Adapted Electroretinogram.

Bioengineering (Basel, Switzerland)·2025

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 17, 2025

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

Published on: July 1, 2016

Ambient lighting alters pattern electroretinogram P50 peak time and spatial sensitivity.

Lisa Tucker¹, Oliver R Marmoy^2,3, Siân E Handley^2,3

¹Clinical and Academic Department of Ophthalmology, Tony Kriss Visual Electrophysiology Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, 40-41 Queens Square, London, UK. lisa.tucker@gosh.nhs.uk.

Documenta Ophthalmologica. Advances in Ophthalmology

|August 14, 2024

Summary

This summary is machine-generated.

Ambient lighting affects pattern electroretinography (PERG) P50 peak time. Lights-on conditions show an earlier P50 peak time, highlighting the need for consistent lighting during PERG recordings.

Keywords:

Ambient background light Contrast Luminance PERG Pattern ERG Room light Spatial sensitivity

More Related Videos

Implantation and Recording of Wireless Electroretinogram and Visual Evoked Potential in Conscious Rats

Implantation and Recording of Wireless Electroretinogram and Visual Evoked Potential in Conscious Rats

Published on: June 29, 2016

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning

Published on: June 9, 2015

Related Experiment Videos

Last Updated: Jun 17, 2025

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

Published on: July 1, 2016

Implantation and Recording of Wireless Electroretinogram and Visual Evoked Potential in Conscious Rats

Implantation and Recording of Wireless Electroretinogram and Visual Evoked Potential in Conscious Rats

Published on: June 29, 2016

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning

Published on: June 9, 2015

Area of Science:

Ophthalmology
Neuroscience
Visual Psychophysics

Background:

Pattern electroretinography (PERG) is a clinical tool assessing retinal function.
Ambient lighting conditions can influence electrophysiological measurements.
Understanding these influences is crucial for accurate PERG interpretation.

Purpose of the Study:

To investigate the impact of ambient lighting on pattern electroretinography (PERG).
To compare PERG P50 peak time under lights-on versus lights-off conditions.

Main Methods:

PERGs were recorded from 21 participants in both lights-on and lights-off conditions.
Stimuli included high-contrast checks of varying sizes and reversal rates.
Data were acquired using averages of 300 trials per condition.

Main Results:

The P50 peak time was significantly earlier by 3 ms in lights-on conditions compared to lights-off.
This effect persisted across different stimulus contrasts and check sizes.
Lights-on P50 peak time for a 50' check width matched lights-off for a 25' check width.

Conclusions:

Ambient lighting significantly alters PERG P50 peak time.
The observed differences may be due to retinal adaptation and altered spatial sensitivity.
Consistent ambient lighting is critical for reliable PERG recording and clinical calibration.