Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mouse Models of Cancer Study

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Genetic architecture of the murine serum metabolome reveals carboxyl esterases as master regulators of circulating fatty acid metabolism.

bioRxiv : the preprint server for biology·2026

Same author

Alzheimer's disease biological domain sub-stratification enhances the precision of functional analyses.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same author

Splicing of ultraconserved poison exons controls mitotic fidelity and stem cell viability.

bioRxiv : the preprint server for biology·2026

Same author

Improve genetic quality control to increase rigor and reproducibility of mouse research.

Science (New York, N.Y.)·2026

Same author

Modeling patient variants of <i>Cnot1</i> and <i>Cdc42bpb</i> results in distinct forms of congenital diaphragmatic hernia in mice.

bioRxiv : the preprint server for biology·2026

Same author

Data-driven prioritization of mouse strains for improved preclinical modeling of rare and common disease.

bioRxiv : the preprint server for biology·2026

Search research articles

Related Experiment Video

Updated: Jun 17, 2025

Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment

Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment

Published on: June 22, 2015

Improving the predictive power of mouse models

Martin Pera¹, Andy Greene¹, Lon Cardon¹

¹The Jackson Laboratory, Bar Harbor, ME, USA.

Nature Biotechnology

|August 14, 2024

Summary

No abstract available in PubMed .

More Related Videos

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station INBEST

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station INBEST

Published on: April 23, 2015

Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

Published on: June 17, 2013

Related Experiment Videos

Last Updated: Jun 17, 2025

Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment

Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment

Published on: June 22, 2015

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station INBEST

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station INBEST

Published on: April 23, 2015

Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

Published on: June 17, 2013