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Updated: Jun 16, 2025

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Characterizing left ventricular systolic dysfunction in sickle cell disease: three contrasting case reports

George Katis1, Sridhar Srinivasan1, Perla Eleftheriou1

  • 1University College Hospital, 235 Euston Road, London NW12BU, UK.

European Heart Journal. Case Reports
|August 15, 2024
PubMed
Summary

Left ventricular systolic dysfunction (LVSD) in sickle cell disease (SCD) has varied causes, including iron overload, non-ischemic dilated cardiomyopathy, and ischemic cardiomyopathy. Understanding these distinct mechanisms is crucial for effective patient treatment.

Keywords:
Cardiac MRICase reportHeart failureLeft ventricular systolic dysfunctionSickle cell disease

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